I was on the mathematics faculty at M.I.T. from 1951 through until I resigned in the spring of 1959.
There are things that tend to moderate with age. Schizophrenia is somewhat like that.
I think mental illness or madness can be an escape also. People don't develop a mental illness because they are in the happiest of situations, usually. One doctor observed that it was rare when people were rich to become schizophrenic. If they were poor or didn't have too much money, then it was more likely.