There are still movies where females are just there to be cool, or they are there to lambaste their husbands and scold. But female comedy characters are changing for the better.
The huge advantage of boarding school is that it throws you into the social fire. Every social interaction I've had since then has been a million times easier. Literally, ever since then, it's all been child's play.
I would never make a purely autobiographical movie, because it would be incredibly boring. But I always bring something. It's usually some emotional truth I've experienced, like in 'Get Him to the Greek,' the relationship between Jonah Hill and Elisabeth Moss, I had certainly had that kind of relationship with a girlfriend.
The worst thing you can do is animate something and then throw it out because it doesn't work story-wise.