I've got big shoes to fill. This is my chance to do something. I have to seize the moment.
The biggest risk is not taking any risk... In a world that is changing really quickly, the only strategy that is guaranteed to fail is not taking risks.
The ego certainly is the biggest obstacle as an artist or performer, so any chance you get to destroy that is really healthy.
What chance does a five-foot-seven billionaire Jew who's divorced really have of becoming president?
The circadian neurons are one of the few circuits in neurobiology where we have a chance to understand at multiple levels how different sets of neurons communicate with each other - including understanding the wiring rules, the biochemical rules, and the functional behavioral rules.
It was a chance encounter with a biotech entrepreneur from Ireland that got me started as an entrepreneur in India, because I partnered this Irish company in setting up India's first biotech company.
The history of the Internet is, in part, a series of opportunities missed: the major record labels let Apple take over the digital-music business; Blockbuster refused to buy Netflix for a mere fifty million dollars; Excite turned down the chance to acquire Google for less than a million dollars.
The performance centre is unbelievable, I've had a chance to go there on a couple of occasions in Orlando as it's only about two hours from my house, and I was completely blown away.
When I was in the gunner's bubble of a B25 bomber, taking off from an aircraft carrier 100 miles off the coast of San Diego, I remember saying to myself how amazing it was to get the chance to do that.
For all their current prestige, Osama bin Laden and the suicide bombers are still regarded in all but the most desperate districts of Gaza or Peshawar as romantics with little chance of more than symbolic victories, however bloody and brutal. That gives both the Middle East and the West a small and distant hope of security.
I totally heard by chance that they were doing the casting for a James Bond movie, and that one of the auditions was taking place in Paris. So I tried myself to contact every name involved in the movie I could possibly find on the IMDb!
One of the great upsides to a national book tour is the chance to break out of television's cocoon and interact directly with the American people.
Every existing thing is born without reason, prolongs itself out of weakness, and dies by chance.
I believe as a born-again Christian that once you've had a chance to drink from the well, it becomes your responsibility to replenish the well.
I continue to work on plays, but I've always felt that you could put a note in a bottle and send it offshore, and you'd have as much chance communicating with people.
It was an unbelievable experience! The brakes, the g-forces and the power of the engine are beyond description. Thanks to BMW and WilliamsF1 for giving me this chance to test. The test team looked after me brilliantly and I learnt plenty.
How can faceless bureaucrats in an intelligence agency deny brave soldiers a chance to tell the truth?
I was a huge fan of Bobby Cox, a huge fan of Chipper Jones and John Smoltz. And just those guys, I grew up watching those guys and often wondered early on in my career if I would ever have the chance to play for the Atlanta Braves, and there it was. God kind of answered my prayers.
Valor is of no service, chance rules all, and the bravest often fall by the hands of cowards.
I always sort of thought, 'I'm probably going to get breast cancer. There's a really good chance.'