There was a time when Pluto - which NASA's New Horizons spacecraft at last explored in 2015, a mission I led - was considered the last planet. We now know there are thousands of other - possibly inhabited - planets.
Each time these pioneers expanded into new realms, they discovered the old ways wouldn't work. Whenever a new domain was inhabited by humans, old survival patterns were left behind and new patterns created.
Whenever I am in Paris, all I want to do is inhale a big plate of cheese. And in New York, my favourite thing is a toasted bagel with cream cheese. Not only do I not avoid carbs, I more or less have them in every meal. When I start denying myself foods, that's when I crave them.
Actually... I'm starting a new thing and rebelling against ridiculously high heels. It's inhumane.
Whoever refuses to remember the inhumanity is prone to new risks of infection.
Deep, unspeakable suffering may well be called a baptism, a regeneration, the initiation into a new state.
It is important to nurture any new ideas and initiatives which can make a difference for Africa.
If you're black and have leukemia, the chances of finding a donor are drastically reduced. I added my name to the register, and lo and behold, six months later, I was asked to donate. I had a week of 'conditioning' where I had to take these pills and injections to create new stem cells in my body.
We need the next generation to be motivated and to push technological boundaries, to seek out new innovations.
Every time you have a new tax, or every time you have to pay really an inordinate amount for a regulation, it's really stifling this country and really stifling American business.
I'm never surprised by the insensitivity of 'The New York Times' editorial board.
My 2005 calendar we actually did a shoot in Lake Las Vegas. Since I had requests do some swimwear and athletic shots we tried them and they came out good so we inserted them into the new calendar.
Eventually I found it had been working all along-but didn't show anything on screen until it had the first full page of text. I inserted 30 new lines, and suddenly my toy said 'hEllO woRlD'. An hour later I understood alphabet shifting rather better!
What unites Sanders, McCarthy, McGovern and Reagan is the unmistakable clarity of their moral convictions, their tendency to outrage, and their insistence that the United States needs to embark on a whole new path.
I have to admit that talking authoritatively about my students' stories can make me feel, at times, like an astronaut who has just landed on a new planet and insists on giving guided tours to its inhabitants.
The mania started with insomnia and not eating and being driven, driven to find an apartment, driven to see everybody, driven to do New York, driven to never shut up.
We have played a critical role in meeting the new safety standards. The Canadian space industry contributed new tools that make the inspection of the space shuttle possible.
We are now on the threshold of a newer movement, with a newer hope and a new inspiration.
I didn't start doing graffiti until two years after I got to New York. Jean Michel Basquiat was one of my main inspirations for doing graffiti. For a year I didn't know who Jean Michel was, but I knew his work.
The new age of terrorism isn't on the battlefield: it's in your own backyard. Whether it's at a concert in France or a restaurant in the United States, terrorism doesn't have to happen in a military installation by any stretch of the imagination.