In the tropical and subtropical regions, endemic malaria takes first place almost everywhere among the causes of morbidity and mortality, and it constitutes the principal obstacle to the acclimatization of Europeans in these regions.
In 1880 at the Military Hospital at Constantine, I discovered, on the edges of the pigmented spherical bodies in the blood of a patient suffering from malaria, filiform elements resembling flagellae which were moving very rapidly, displacing the neighbouring red cells.
